dietary supplement, 90 capsules/1 package.
Carnitine is an amino acid derivative and a micronutrient that plays a key role in intermediary metabolism, its main function being the transport of long-chain fatty acids into the mitochondrial matrix, where fatty acid oxidation occurs. Other functions of carnitine include maintaining membrane integrity and reducing lactate production. Human muscles contain large amounts of carnitine, but this depends on the uptake of this compound from the bloodstream due to the muscle's inability to synthesize carnitine. Mitochondrial fatty acid oxidation is an important source of energy for muscle metabolism, especially during physical exercise. Our bodies obtain carnitine primarily from the diet, primarily from animal-derived foods such as red meat, chicken, fish, and dairy products. Only 25% of carnitine comes from endogenous synthesis. Carnitine biosynthesis requires two essential amino acids: L-lysine and L-methionine. The total carnitine content in the human body is estimated to be approximately 300 mg/kg, of which approximately 95% is stored intracellularly in the heart and skeletal muscle, with the remainder in the liver, kidneys, and plasma. Circulating plasma carnitine accounts for only 0.5% of the total body carnitine. In other words, muscle is likely the primary target for carnitine transport among various peripheral tissues. Approximately 90–95% of total carnitine is concentrated in muscle, with a muscle-to-plasma carnitine concentration ratio of approximately 50:11. L-carnitine is used as a dietary supplement by recreationally active individuals, as well as competitive and highly trained athletes. The main function of L-carnitine is to transport long-chain fatty acids into the mitochondrial matrix for conversion into energy. L-carnitine also participates in the regulation of metabolic pathways that are important for skeletal muscle protein balance (proteolysis and protein synthesis). 2. L-carnitine is popularly used as an ergogenic aid, with the main assumption being that increasing muscle carnitine content will increase muscle fat oxidation and delay muscle glycogen depletion. 3. It is believed (and of course, there is scientific evidence for this) that L-carnitine plays a significant role in increasing endurance and recovery from fatigue.
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